Rechallenge with anti-EGFR therapy to extend the continuum of care in patients with metastatic colorectal cancer

In patients with RAS wild-type metastatic colorectal cancer (mCRC), an anti-epidermal growth factor receptor (EGFR) monoclonal antibody plus chemotherapy is a standard option ORG RELIEFIBRE POWDER TROPIC for treatment in the first-line setting.Patients who progress while on treatment with anti-EGFR-based therapy can be resistant to further anti-EGF

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Interleukin-10 induces expression of CD39 on CD8+T cells to potentiate anti-PD1 efficacy in EGFR-mutated non-small cell lung cancer

Background Anti-PD-1(L1) therapies are less efficacious in patients with EGFR-mutated non-small-cell lung cancer.However, the underlying mechanism is poorly understood.Methods The characteristics of T cells in EGFR-mutated and wild-type tumors were analyzed based on The Cancer Genome Atlas database and clinical samples.Plasma levels of 8 T-cell-rel

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Yogurt as an Alternative Ingredient to Improve the Functional and Nutritional Properties of Gluten-Free Breads

Absence of gluten in bakery goods is a technological challenge, generating gluten-free breads with low functional and nutritional properties.However, these issues can be minimized using new protein sources, by the addition of nutritional added-value products.Fresh yogurt represents an interesting approach since it is a source of protein, polysaccha

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